Daily Archives: December 15, 2014

In the blood, DNA changes anticipate future cancer

A common, pre-cancerous state can precede cancer by many years and is readily detectable by DNA sequencing, according to a new paper by Giulio Genovese and colleagues in the New England Journal of Medicine.

Genovese discovered somatic (acquired) mutations from their presence at unusual

allelic fractions – reflecting that they are present in some, but not all, of the cells in a person’s blood.