Yearly Archives: 2014

In the blood, DNA changes anticipate future cancer

A common, pre-cancerous state can precede cancer by many years and is readily detectable by DNA sequencing, according to a new paper by Giulio Genovese and colleagues in the New England Journal of Medicine.

DNA replication varies among humans

A process as fundamental as replication of a genome varies from person – shaped by common, inherited genetic variation that can also affect risk of cancer. The work is described in a new paper by Amnon Koren and colleagues in Cell.

Found at last: the human genome’s missing pieces

The mystery had tantalized geneticists for 15 years: scores of genes and millions of bases of human DNA sequence had no home on maps of the human genome. Where in the human genome were they hiding? The mystery is solved – with mathematics – in a paper by Giulio Genovese and colleagues in Nature Genetics.